ClickChemistryTools點(diǎn)擊化學(xué)銅配體THPTA

中文介紹：

THPTA（三羥丙基三唑基甲胺）是一種水溶性、非常有效的加速配體，用于銅催化的炔烴-疊氮化物點(diǎn)擊化學(xué)反應(yīng)（CuAAC）。除了大大提高CuAAC的速率外，THPTA還最大限度地減少了對(duì)所探測細(xì)胞或生物體生理狀態(tài)的擾動(dòng)，并通過進(jìn)一步降低催化劑配方中的Cu負(fù)載量，允許有效的生物偶聯(lián)與抑制細(xì)胞細(xì)胞毒性。水溶性THPTA配體允許整個(gè)反應(yīng)在水中運(yùn)行，進(jìn)一步簡化了點(diǎn)擊化學(xué)。

英文介紹：

THPTA (tris-hydroxypropyltriazolylmethylamine) is a water-soluble, very effective accelerating ligand for copper-catalyzed Alkyne-Azide click chemistry reactions (CuAAC). In addition to greatly enhancing the rate of CuAAC, THPTA minimizes perturbations to the physiological state of the cells or organisms probed and allows for the effective bioconjugation with suppressed cell cytotoxicity by further lowering Cu loading in the catalyst formulation. The water-soluble THPTA ligand further simplifies click chemistry by allowing the entire reaction to be run in water.

產(chǎn)品參數(shù)：

參考文獻(xiàn)：

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